OPTIMIZATION OF CROSCARMELLOSE AND SODIUM STARCH GLYCOLATE ON ORALLY DISINTEGRATING METOCLOPRAMIDE HCL TABLETS

• Main Authors: Endang Diyah Ikasari (Author), Intan Martha Cahyani (Author), Deby Melinda Collusy (Author)
• 格式: 图书
• 出版: Universitas Muhammadiyah Magelang, 2022-12-01T00:00:00Z.
• 主题: article
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Dosage form of metoclopramide HCl which has high solubility but low permeability is Orally Disintegrating Tablet (ODT), because  can decrease first-pass-effect metabolism so that its bioavailability and effectiveness increase. Superdisintegrant is an excipient that has a major role in the formulatio...