Lentinan improved the efficacy of vaccine against Trichinella spiralis in an NLRP3 dependent manner.

• Main Authors: Xuemin Jin (Author), Xiaolei Liu (Author), Jing Ding (Author), Lixiao Zhang (Author), Yaming Yang (Author), Xuelin Wang (Author), Yong Yang (Author), Mingyuan Liu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is an urgent need for the development of new, improved vaccine adjuvants against T. spiralis infection. Polysaccharides are effective, safe, and biodegradable as adjuvant. In our study, we first observed the protective efficacy of lentinan as adjuvant against helminth T. spiralis infection. Re...