Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives

• Hoofdauteurs: Hao Sun (Auteur), Yingmei Li (Auteur), Peng Zhang (Auteur), Haizhou Xing (Auteur), Song Zhao (Auteur), Yongping Song (Auteur), Dingming Wan (Auteur), Jifeng Yu (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2022-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Toll-like receptors (TLRs) are a large family of proteins that are expressed in immune cells and various tumor cells. TLR7/8 are located in the intracellular endosomes, participate in tumor immune surveillance and play different roles in tumor growth. Activation of TLRs 7 and 8 triggers ind...