Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives

• मुख्य लेखकों: Hao Sun (लेखक), Yingmei Li (लेखक), Peng Zhang (लेखक), Haizhou Xing (लेखक), Song Zhao (लेखक), Yongping Song (लेखक), Dingming Wan (लेखक), Jifeng Yu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Toll-like receptors (TLRs) are a large family of proteins that are expressed in immune cells and various tumor cells. TLR7/8 are located in the intracellular endosomes, participate in tumor immune surveillance and play different roles in tumor growth. Activation of TLRs 7 and 8 triggers ind...