Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives

• Asıl Yazarlar: Hao Sun (Yazar), Yingmei Li (Yazar), Peng Zhang (Yazar), Haizhou Xing (Yazar), Song Zhao (Yazar), Yongping Song (Yazar), Dingming Wan (Yazar), Jifeng Yu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Toll-like receptors (TLRs) are a large family of proteins that are expressed in immune cells and various tumor cells. TLR7/8 are located in the intracellular endosomes, participate in tumor immune surveillance and play different roles in tumor growth. Activation of TLRs 7 and 8 triggers ind...