Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives

• Main Authors: Hao Sun (Author), Yingmei Li (Author), Peng Zhang (Author), Haizhou Xing (Author), Song Zhao (Author), Yongping Song (Author), Dingming Wan (Author), Jifeng Yu (Author)
• Format: Book
• Published: BMC, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Toll-like receptors (TLRs) are a large family of proteins that are expressed in immune cells and various tumor cells. TLR7/8 are located in the intracellular endosomes, participate in tumor immune surveillance and play different roles in tumor growth. Activation of TLRs 7 and 8 triggers ind...