Antiepileptogenic and Neuroprotective Effects of Pergularia daemia on Pilocarpine Model of Epilepsy

• Main Authors: Antoine K. Kandeda (Author), Germain S. Taiwe (Author), Fleur C. O. Moto (Author), Gwladys T. Ngoupaye (Author), Gisele C. N. Nkantchoua (Author), Jacqueline S. K. Njapdounke (Author), Jean P. O. Omam (Author), Simon Pale (Author), Nadege Kouemou (Author), Elisabeth Ngo Bum (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, we investigated antiepileptogenic and neuroprotective effects of the aqueous extract of Pergularia daemia roots (PDR) using in vivo and in vitro experimental models. In in vivo studies, status epilepticus caused by pilocarpine injection triggers epileptogenesis which evolves during ab...