Analysis of proteins associated with the expression of cyclooxygenase-2 and the biosynthesis of PGE2 in breast cancer cells with different metastatic potential

• Main Authors: V. E. Shevchenko (Author), M. A. Taipov (Author), S. V. Kovalev (Author), N. E. Arnotskaya (Author), O. M. Pavlova (Author), I. A. Kudryavtsev (Author), Z. N. Nikiforova (Author)
• Format: Book
• Published: ABV-press, 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The proteome of lysates of the breast tumor cell lines MCF-7, BT-474, and ZR-75-1 was mapped, resulting in the sequence of 340 proteins. The proteins associated with the biosynthesis of PGE2 and with the regulation of cyclooxygenase-2 expression were identified and their relative expression levels w...