Glioma-targeted delivery of exosome-encapsulated antisense oligonucleotides using neural stem cells

• मुख्य लेखकों: Tomasz Adamus (लेखक), Chia-Yang Hung (लेखक), Chunsong Yu (लेखक), Elaine Kang (लेखक), Mohamed Hammad (लेखक), Linda Flores (लेखक), Sergey Nechaev (लेखक), Qifang Zhang (लेखक), Joanna Marie Gonzaga (लेखक), Kokilah Muthaiyah (लेखक), Piotr Swiderski (लेखक), Karen S. Aboody (लेखक), Marcin Kortylewski (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2022-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Tropism of neural stem cells (NSCs) to hypoxic tumor areas provides an opportunity for the drug delivery. Here, we demonstrate that NSCs effectively transport antisense oligonucleotides (ASOs) targeting oncogenic and tolerogenic signal transducer and activator of transcription 3 (STAT3) protein into...