Multicomponent synthesis of some new (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamates and their in vitro anti-proliferative activity against CaSki, MDA-MB-231 and SK-Lu-1 tumour cells as apoptosis inducing agents without necrosis

• Κύριοι συγγραφείς: Sujay Laskar (Συγγραφέας), Luis Sánchez-Sánchez (Συγγραφέας), Manuel López-Ortiz (Συγγραφέας), Hugo López-Muñoz (Συγγραφέας), María L. Escobar-Sánchez (Συγγραφέας), Arturo T. Sánchez (Συγγραφέας), Ignacio Regla (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Identification of a new class of antitumor agent capable to induce apoptosis without triggering necrotic cell death event is challenging. The present communication describes the multicomponent synthesis of seven new (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamates and their in vitro antiproli...