PTPN22 gene and IL2RA rs11594656, rs2104286 gene variants: additional insights of polygenic single-nucleotide polymorphisms' pattern among Egyptian children with type 1 diabetes

• Main Authors: Soheir S. Abou El Ella (Author), Maha A. Tawfik (Author), Zeinab Sabri Mohammed (Author), Naglaa Fathy Barseem (Author)
• Formato: Libro
• Publicado: SpringerOpen, 2021-11-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Abstract Background Type 1 diabetes mellitus (T1D) results from environmental and genetic factors. We aimed to investigate the distribution of PTPN22, IL2RA rs11594656, and rs2104286 variants and its association with T1D in children. A case-control study conducted on 100 diabetic patients and 100 co...