Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resistant Staphylococcus aureus

• Main Authors: Genzhu Wang (Author), Liang Li (Author), Xiukun Wang (Author), Xue Li (Author), Youwen Zhang (Author), Jie Yu (Author), Jiandong Jiang (Author), Xuefu You (Author), Yan Q. Xiong (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection. Staphylococcal accessory regulator A (SarA), a global virulence regulator, plays a critical role...