A quantitative structure-activity relationship (QSAR) study of some diaryl urea derivatives of B-RAF inhibitors

• Main Authors: Sedighe Sadeghian-Rizi (Author), Amirhossein Sakhteman (Author), Farshid Hassanzadeh (Author)
• Formato: Libro
• Publicado: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

In the current study, both ligand-based molecular docking and receptor-based quantitative structure activity relationships (QSAR) modeling were performed on 35 diaryl urea derivative inhibitors of V600E B-RAF. In this QSAR study, a linear (multiple linear regressions) and a nonlinear (partial least...