miR-210 Protects Renal Cell Against Hypoxia-induced Apoptosis by Targeting HIF-1 Alpha

• Main Authors: Li-Li Liu (Author), Dahu Li (Author), Yun-Ling He (Author), Yan-Zhao Zhou (Author), Sheng-Hui Gong (Author), Li-Ying Wu (Author), Yong-Qi Zhao (Author), Xin Huang (Author), Tong Zhao (Author), Lun Xu (Author), Kui-Wu Wu (Author), Ming-Gao Li (Author), Ling-Ling Zhu (Author), Ming Fan (Author)
• Format: Book
• Published: BMC, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The kidney is vulnerable to hypoxia-induced injury. One of the mechanisms underlying this phenomenon is cell apoptosis triggered by hypoxia-inducible factor-1- α (HIF-1α) activation. MicroRNA-210 (miR-210) is known to be induced by HIF-1α and can regulate various pathological processes, but...