Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer's disease

• Main Authors: Wen-Yu Wu (Author), Yu-Chen Dai (Author), Nian-Guang Li (Author), Ze-Xi Dong (Author), Ting Gu (Author), Zhi-Hao Shi (Author), Xin Xue (Author), Yu-Ping Tang (Author), Jin-Ao Duan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) is a neurodegenerative disorder, which is complex and progressive; it has not only threatened the health of elderly people, but also burdened the whole social medical and health system. The available therapy for AD is limited and the efficacy remains unsatisfactory. In...