Recent Methods for Measuring Dopamine D3 receptor Occupancy In Vivo: Importance for Drug Development

• Main Authors: Bernard eLe Foll (Author), Alan eWilson (Author), Ariel eGraff (Author), Isabelle eBoileau (Author), Patricia eDi Ciano (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is considerable interest in developing highly selective dopamine D3 receptor ligands for a variety of mental health disorders. Dopamine D3 receptors have been implicated in Parkinson's Disease, schizophrenia, anxiety, depression, and substance use disorders. The most concrete evidence sug...