Pharmacokinetics and Pharmacodynamics of Meropenem by Extended or Continuous Infusion in Low Body Weight Critically Ill Patients

• Main Authors: Sonia Luque (Author), Adela Benítez-Cano (Author), Leire Larrañaga (Author), Luisa Sorlí (Author), María Eugenia Navarrete (Author), Nuria Campillo (Author), Jesús Carazo (Author), Isabel Ramos (Author), Ramón Adalia (Author), Santiago Grau (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Background</i>: Pathophysiological changes such as extreme body weights in critically ill patients with severe infections may alter the pharmacokinetics (PK) of antimicrobials, leading to treatment failure or toxicity. There are almost no PK data on meropenem in critically ill patient...