Subtype selective fluorescent ligands based on ICI 118,551 to study the human β2‐adrenoceptor in CRISPR/Cas9 genome‐edited HEK293T cells at low expression levels

• Váldodahkkit: Joëlle Goulding (Dahkki), Sarah J. Mistry (Dahkki), Mark Soave (Dahkki), Jeanette Woolard (Dahkki), Stephen J. Briddon (Dahkki), Carl W. White (Dahkki), Barrie Kellam (Dahkki), Stephen J. Hill (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Wiley, 2021-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Fluorescent ligand technologies have proved to be powerful tools to improve our understanding of ligand‐receptor interactions. Here we have characterized a small focused library of nine fluorescent ligands based on the highly selective β2‐adrenoceptor (β2AR) antagonist ICI 118,551. The majo...