Subtype selective fluorescent ligands based on ICI 118,551 to study the human β2‐adrenoceptor in CRISPR/Cas9 genome‐edited HEK293T cells at low expression levels

Subtype selective fluorescent ligands based on ICI 118,551 to study the human β2‐adrenoceptor in CRISPR/Cas9 genome‐edited HEK293T cells at low expression levels

Abstract Fluorescent ligand technologies have proved to be powerful tools to improve our understanding of ligand‐receptor interactions. Here we have characterized a small focused library of nine fluorescent ligands based on the highly selective β2‐adrenoceptor (β2AR) antagonist ICI 118,551. The majo...

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Main Authors: Joëlle Goulding (Author), Sarah J. Mistry (Author), Mark Soave (Author), Jeanette Woolard (Author), Stephen J. Briddon (Author), Carl W. White (Author), Barrie Kellam (Author), Stephen J. Hill (Author)
Format: Book
Published: Wiley, 2021-05-01T00:00:00Z.
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