Defective Leukocyte β2 Integrin Expression and Reactive Oxygen Species Production in Neonates

• Main Authors: Irma Capolupo (Author), Domenico Umberto De Rose (Author), Roberto Pascone (Author), Olivier Danhaive (Author), Marcello Orzalesi (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neonates are highly susceptible to bacterial infections, which represent a major source of mortality and morbidity in this age category. It is recognized that β2 integrins play a critical role in innate immunity by mediating leukocyte vascular adhesion, transmigration and bacterial phagocytosis. The...