Targeting female flight for genetic control of mosquitoes.

• Main Authors: David Navarro-Payá (Author), Ilona Flis (Author), Michelle A E Anderson (Author), Philippa Hawes (Author), Ming Li (Author), Omar S Akbari (Author), Sanjay Basu (Author), Luke Alphey (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aedes aegypti Act4 is a paralog of the Drosophila melanogaster indirect flight muscle actin gene Act88F. Act88F has been shown to be haploinsufficient for flight in both males and females (amorphic mutants are dominant). Whereas Act88F is expressed in indirect flight muscles of both males and female...