Intestinal GPR119 activation by microbiota-derived metabolites impacts feeding behavior and energy metabolism

• Main Authors: Miki Igarashi (Author), Tetsuhiko Hayakawa (Author), Haruka Tanabe (Author), Keita Watanabe (Author), Akari Nishida (Author), Ikuo Kimura (Author)
• Format: Book
• Published: Elsevier, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The gastrointestinal tract affects physiological activities and behavior by secreting hormones and generating signals through the activation of nutrient sensors. GPR119, a lipid sensor, is indirectly involved in the secretion of incretins, such as glucagon-like peptide-1 and glucose-depen...