Interleukin-18 in chronic pain: Focus on pathogenic mechanisms and potential therapeutic targets

• Main Authors: Jie Ju (Author), Zheng Li (Author), Xiaoqian Jia (Author), Xiaoling Peng (Author), Jihong Wang (Author), Feng Gao (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic pain has been proven to be an independent disease, other than an accompanying symptom of certain diseases. Interleukin-18 (IL-18), a pro-inflammatory cytokine with pleiotropic biological effects, participates in immune modulation, inflammatory response, tumor growth, as well as the process o...