Metabolomics and integrated network pharmacology analysis reveal SNKAF decoction suppresses cell proliferation and induced cell apoptisis in hepatocellular carcinoma via PI3K/Akt/P53/FoxO signaling axis

• Main Authors: Wei Guo (Author), Xiaohui Yao (Author), Siyuan Lan (Author), Chi Zhang (Author), Hanhan Li (Author), Zhuangzhong Chen (Author), Ling Yu (Author), Guanxian Liu (Author), Yuan Lin (Author), Shan Liu (Author), Hanrui Chen (Author)
• Format: Book
• Published: BMC, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background There is no comprehensive treatment method for hepatocellular carcinoma (HCC); hence, research and development are still focused on systemic therapies, including drugs. Sinikangai fang (SNKAF) decoction, a classic Chinese herbal prescription, has been widely used to treat liver c...