Combination effect of doxorubicin and HIF inhibitor on MCF-7 CD44+/CD24- subpopulation cells in hypoxic condition

• Main Authors: Azadeh Rasouli (Author), Shima Aliebrahimi (Author), Vahideh Montazeri (Author), Mohammad Hossein Ghahremani (Author), Seyed Nasser Ostad (Author)
• Format: Book
• Published: Universidade de São Paulo, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Hypoxia-inducible factors (HIFs) and cancer stem cells (CSCs) are two challenging causes of radiotherapy and chemotherapy resistance, leading to most cases of failure and recurrence in breast cancer therapy. This study was conducted to investigated the inhibitory effect of combination thera...