Roxatidine- and Cimetidine-Induced Angiogenesis Inhibition Suppresses Growth of Colon Cancer Implants in Syngeneic Mice

• Main Authors: Kazuyoshi Tomita (Author), Kazuki Izumi (Author), Susumu Okabe (Author)
• Formato: Libro
• Publicado: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

ABSTRACT: Cimetidine is known to suppress the growth of several tumors, including gastrointestinal cancer, in humans and animals. Nonetheless, whether other histamine H2-receptor antagonists exert such tumor suppressive effects remains unclear. The effect of roxatidine acetate hydrochloride (roxatid...