Acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA

• Main Authors: Nour Zeaiter (Author), Laura Belot (Author), Valérie Cunin (Author), Roland Abi Nahed (Author), Malgorzata Tokarska-Schlattner (Author), Audrey Le Gouellec (Author), Carlo Petosa (Author), Saadi Khochbin (Author), Uwe Schlattner (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acetyl and other acyl groups from different short-chain fatty acids (SCFA) competitively modify histones at various lysine sites. To fully understand the functional significance of such histone acylation, a key epigenetic mechanism, it is crucial to characterize the cellular sources of the correspon...