In vitro and in vivo growth inhibitory activities of cryptolepine hydrate against several Babesia species and Theileria equi.

• Main Authors: Gaber El-Saber Batiha (Author), Amany Magdy Beshbishy (Author), Luay M Alkazmi (Author), Eman H Nadwa (Author), Eman K Rashwan (Author), Naoaki Yokoyama (Author), Ikuo Igarashi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Piroplasmosis treatment has been based on the use of imidocarb dipropionate or diminazene aceturate (DA), however, their toxic effects. Therefore, the discovery of new drug molecules and targets is urgently needed. Cryptolepine (CRY) is a pharmacologically active plant alkaloid; it has significant p...