Untangling the Web of Systemic Autoinflammatory Diseases

• Main Authors: Donato Rigante (Author), Giuseppe Lopalco (Author), Antonio Vitale (Author), Orso Maria Lucherini (Author), Francesco Caso (Author), Caterina De Clemente (Author), Francesco Molinaro (Author), Mario Messina (Author), Luisa Costa (Author), Mariangela Atteno (Author), Franco Laghi-Pasini (Author), Giovanni Lapadula (Author), Mauro Galeazzi (Author), Florenzo Iannone (Author), Luca Cantarini (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The innate immune system is involved in the pathophysiology of systemic autoinflammatory diseases (SAIDs), an enlarging group of disorders caused by dysregulated production of proinflammatory cytokines, such as interleukin-1β and tumor necrosis factor-α, in which autoreactive T-lymphocytes and autoa...