Pretargeted Imaging beyond the Blood-Brain Barrier-Utopia or Feasible?
Pretargeting is a promising nuclear imaging technique that allows for the usage of antibodies (Abs) with enhanced imaging contrast and reduced patient radiation burden. It is based on bioorthogonal chemistry with the tetrazine ligation-a reaction between <i>trans</i>-cyclooctenes (TCOs)...
Saved in:
Main Authors: | Sara Lopes van den Broek (Author), Vladimir Shalgunov (Author), Rocío García Vázquez (Author), Natalie Beschorner (Author), Natasha S. R. Bidesi (Author), Maiken Nedergaard (Author), Gitte M. Knudsen (Author), Dag Sehlin (Author), Stina Syvänen (Author), Matthias M. Herth (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Clearing and Masking Agents in Pretargeting Strategies
by: Markus Staudt, et al.
Published: (2023) -
Development of <sup>18</sup>F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging
by: Rocío García-Vázquez, et al.
Published: (2022) -
Recent Advances in the Development of Tetrazine Ligation Tools for Pretargeted Nuclear Imaging
by: Rocío García-Vázquez, et al.
Published: (2022) -
Synthesis and evaluation of fluorine-18 labelled tetrazines as pre-targeting imaging agents for PET
by: Eva Schlein, et al.
Published: (2024) -
Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody
by: Eva Schlein, et al.
Published: (2024)