Downregulated XBP-1 Rescues Cerebral Ischemia/Reperfusion Injury-Induced Pyroptosis via the NLRP3/Caspase-1/GSDMD Axis

• Main Authors: Yueting Zhang (Author), Zhihui Yao (Author), Yan Xiao (Author), Xiaoling Zhang (Author), Jiaxin Liu (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2022-01-01T00:00:00Z.
• Fag: article
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Ischemic stroke is a major condition that remains extremely problematic to treat. A cerebral reperfusion injury becomes apparent after an ischemic accident when reoxygenation of the afflicted area produces pathological side effects that are different than those induced by the initial oxygen and nutr...