Synthesis, molecular modeling, anti-cancer and COX-1/2 inhibitory activities of novel thiazolidinones containing benzothiazole core

• Main Authors: Necla Kulabas (Author), Cansu Tamniku Guven (Author), Merve Duracık (Author), Ozlem Bingol Ozakpınar (Author), İlkay Kucukguzel (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, new 1,3-thiazolidin-4-one derivatives containing arylmethylene groups in the 5-position were obtained from 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine (riluzole). Synthesized compounds were characterized by spectral data and elemental analysis. In vitro, cytotoxic activities of the...