Synthesis and kinetic studies of mutual azo prodrugs of 5-aminosalicylic acid with sulfamethoxazole and trimethoprim as models for colon targeting

In this study, two mutual azo prodrugs were synthesized for colon targeting in a treatment of colonic diverticular disease. The first was synthesized by coupling sulfamethoxazole with salicylic acid; the second was synthesized by coupling one mole of trimethoprim with two moles of salicylic acid. In...

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Autore principale: Yasser Fakri Mustafa (Autore)
Natura: Libro
Pubblicazione: University of Mosul, 2010-12-01T00:00:00Z.
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