Synthesis and kinetic studies of mutual azo prodrugs of 5-aminosalicylic acid with sulfamethoxazole and trimethoprim as models for colon targeting
In this study, two mutual azo prodrugs were synthesized for colon targeting in a treatment of colonic diverticular disease. The first was synthesized by coupling sulfamethoxazole with salicylic acid; the second was synthesized by coupling one mole of trimethoprim with two moles of salicylic acid. In...
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University of Mosul,
2010-12-01T00:00:00Z.
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A1234.567 |
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