Crocetin Protected Human Hepatocyte LO2 Cell From TGF-β-Induced Oxygen Stress and Apoptosis but Promoted Proliferation and Autophagy via AMPK/m-TOR Pathway

ObjectiveTo investigate the protective effects of crocetin against transforming growth factor-β (TGF-β)-induced injury in LO2 cells.MethodsHuman hepatocyte LO2 cells were pre-treated with crocetin (10 μM) for 6, 12, and 24 h, and then induced by TGF-β. Proliferation, oxidative stress, apoptosis, aut...

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Main Authors: Hongxing Guo (Author), Chenyu Ruan (Author), Xiuhong Zhan (Author), Hao Pan (Author), Yumei Luo (Author), Ke Gao (Author)
Format: Book
Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
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