Metabolic Profiling of a CB2 Agonist, AM9338, Using LC-MS and Microcoil-NMR: Identification of a Novel Dihydroxy Adamantyl Metabolite

Adamantyl groups are key structural subunit commonly used in many marketed drugs targeting diseases ranging from viral infections to neurological disorders. The metabolic disposition of adamantyl compounds has been mostly studied using LC-MS based approaches. However, metabolite quantities isolated...

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Main Authors: Chandrashekhar Honrao (Author), Xiaoyu Ma (Author), Shashank Kulkarni (Author), Vinit Joshi (Author), Michael Malamas (Author), Alexander Zvonok (Author), JodiAnne Wood (Author), David Strand (Author), Jason J. Guo (Author), Alexandros Makriyannis (Author)
Format: Book
Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
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3rd Floor Main Library

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