EGFR Amplification and Glioblastoma Stem-Like Cells

• Main Authors: Katrin Liffers (Author), Katrin Lamszus (Author), Alexander Schulte (Author)
• פורמט: ספר
• יצא לאור: Hindawi Limited, 2015-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Glioblastoma (GBM), the most common malignant brain tumor in adults, contains a subpopulation of cells with a stem-like phenotype (GS-cells). GS-cells can be maintained in vitro using serum-free medium supplemented with epidermal growth factor, basic fibroblast growth factor-2, and heparin. However,...