Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug.

• المؤلفون الرئيسيون: Jennifer Keiser (مؤلف), Lucienne Tritten (مؤلف), Angelika Silbereisen (مؤلف), Benjamin Speich (مؤلف), Roberto Adelfio (مؤلف), Mireille Vargas (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses. The re-evaluation of old, forgotten drugs is a promising strategy to...