Aptamer-programmable adeno-associated viral vectors as a novel platform for cell-specific gene transfer

Adeno-associated viruses (AAVs) are commonly used for in vivo gene therapy. Nevertheless, the wide tropism that characterizes these vectors limits specific targeting to a particular cell type or tissue. Here, we developed new chemically modified AAV vectors (Nε-AAVs) displaying a single site substit...

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Main Authors: Francesco Puzzo (Author), Chuanling Zhang (Author), Bethany Powell Gray (Author), Feijie Zhang (Author), Bruce A. Sullenger (Author), Mark A. Kay (Author)
Format: Book
Published: Elsevier, 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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