Role of Folic Acid in the Therapeutic Action of Nanostructured Porous Silica Functionalized with Organotin(IV) Compounds against Different Cancer Cell Lines

• Main Authors: Diana Díaz-García (Author), Karla Montalbán-Hernández (Author), Irene Mena-Palomo (Author), Patriciu Achimas-Cadariu (Author), Antonio Rodríguez-Diéguez (Author), Eduardo López-Collazo (Author), Sanjiv Prashar (Author), Karina Ovejero Paredes (Author), Marco Filice (Author), Eva Fischer-Fodor (Author), Santiago Gómez-Ruiz (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The synthesis, characterization and cytotoxic activity against different cancer cell lines of various mesoporous silica-based materials containing folate targeting moieties and a cytotoxic fragment based on a triphenyltin(IV) derivative have been studied. Two different mesoporous nanostructured sili...