Nanopore sequencing for the screening of myeloid and lymphoid neoplasms with eosinophilia and rearrangement of PDGFRα, PDGFRβ, FGFR1 or PCM1-JAK2

• Main Authors: Simone Romagnoli (Author), Niccolò Bartalucci (Author), Francesca Gesullo (Author), Manjola Balliu (Author), Stefania Bonifacio (Author), Anair Graciela Lema Fernandez (Author), Francesco Mannelli (Author), Davide Bolognini (Author), Elisabetta Pelo (Author), Cristina Mecucci (Author), Paola Guglielmelli (Author), Alessandro Maria Vannucchi (Author)
• Format: Book
• Published: BMC, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Eosinophilia represents a group of diseases with heterogeneous pathobiology and clinical phenotypes. Among the alterations found in primary Eosinophilia, gene fusions involving PDGFRα, PDGFRβ, FGFR1 or JAK2 represent the biomarkers of WHO-defined "myeloid and lymphoid neoplasms with eo...