USP30: Structure, Emerging Physiological Role, and Target Inhibition

• Asıl Yazarlar: Feng Wang (Yazar), Yu Gao (Yazar), Lihui Zhou (Yazar), Junhao Chen (Yazar), Zhiyan Xie (Yazar), Zifan Ye (Yazar), Yanfeng Wang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Ubiquitin-specific protease 30 (USP30) is a deubiquitinating enzyme (DUB) belonging to the USP subfamily, which was found localized in the mitochondrial outer membrane and peroxisomes owing to its unique transmembrane domain. Structural study revealed that USP30 employed a unique catalytic triad and...