Long-Term Paracetamol Treatment Impairs Cognitive Function and Brain-Derived Neurotrophic Factor in Adult Rat Brain

• Principais autores: Laddawan Lalert (Autor), Nutnicha Tantarungsee (Autor), Tipthanan Chotipinit (Autor), Wilawan Ji-au (Autor), Anan Srikiatkhachorn (Autor), Supang Maneesri-le Grand (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2023-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Paracetamol (acetaminophen, APAP) is known as a safe pain reliever; however, its negative effects on the central nervous system have gradually been reported. We examined alterations in learning and memory, and brain-derived neurotrophic factor (BDNF) expression in the frontal cortex and hippocampus...