Molecular profile of the Lynch Syndrome in the Republic of Macedonia

• Autori principali: Marija Hiljadnikova-Bajro (Autore), Toni Josifovski (Autore), Milco Panovski (Autore), Aleksandar J. Dimovski (Autore)
• Natura: Libro
• Pubblicazione: University Ss Cyril and Methodius in Skopje, Faculty of Pharmacy and Macedonian Pharmaceutical Association, 2012-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The most frequent type of hereditary colorectal cancer, the one occurring in the setting of the Lynch syndrome (LS) is considered a phenotypic manifestation of a germline defect in the mismatch repair mechanism i.e. in the MLH1, MSH2, MSH6 or PMS2 gene. Aiming towards establishment of a standardized...