Thermodynamics of clay-drug complex dispersions: Isothermal titration calorimetry and high-performance liquid chromatography

• Main Authors: Ana-Maria Totea (Author), Juan Sabin (Author), Irina Dorin (Author), Karl Hemming (Author), Peter R. Laity (Author), Barbara R. Conway (Author), Laura Waters (Author), Kofi Asare-Addo (Author)
• Format: Book
• Published: Elsevier, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An understanding of the thermodynamics of the complexation process utilized in sustaining drug release in clay matrices is of great importance. Several characterisation techniques as well as isothermal calorimetry were utilized in investigating the adsorption process of a model cationic drug (diltia...