Preparation of a mesoporous silica-based nano-vehicle for dual DOX/CPT pH-triggered delivery

• Główni autorzy: Maria C. Llinàs (Autor), Gabriel Martínez-Edo (Autor), Anna Cascante (Autor), Irene Porcar (Autor), Salvador Borrós (Autor), David Sánchez-García (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

A dual doxorubicin/camptothecin (DOX/CPT) pH-triggered drug delivery mesoporous silica nanoparticle (MSN)-based nano-vehicle has been prepared. In this drug-delivery system (DDS), CPT is loaded inside the pores of the MSNs, while DOX is covalently attached to the surface of an aldehyde-functionalize...