Potent Platinum(IV) Prodrugs That Incorporate a Biotin Moiety to Selectively Target Cancer Cells

Four platinum(IV) prodrugs incorporating a biotin moiety to selectively target cancer cells were synthesised, characterised, and their biological activity assessed. All complexes exhibited exceptional in vitro cytotoxicity against a panel of cancer cell lines, with [Pt(5,6-dimethyl-1,10-phenanthroli...

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Main Authors: Aleen Khoury (Author), Jennette A. Sakoff (Author), Jayne Gilbert (Author), Shawan Karan (Author), Christopher P. Gordon (Author), Janice R. Aldrich-Wright (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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