Increased Free Radical Generation during the Interaction of a Quinone-Quinoline Chelator with Metal Ions and the Enhancing Effect of Light

• Hlavní autoři: Olga Yu. Selyutina (Autor), Simon V. Babenko (Autor), Irina A. Slepneva (Autor), Nikolay E. Polyakov (Autor), George J. Kontoghiorghes (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2023-08-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Schiff bases and similar molecules forming metal complexes may cause redox effects, which may also be influenced by light. Anthraquinones such as doxorubicin and idarubicin are widely used antitumor agents, which can generate reactive oxygen species (ROS), stimulated by both the presence of iron and...