Impact of Poloxamer on Crystal Nucleation and Growth of Amorphous Clotrimazole

• Main Authors: Jie Zhang (Author), Ziqing Yang (Author), Liquan Luo (Author), Kang Li (Author), Taotao Zi (Author), Junjie Ren (Author), Lei Pan (Author), Ziyue Wang (Author), Zihao Wang (Author), Minzhuo Liu (Author), Zhihong Zeng (Author)
• Formato: Libro
• Publicado: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Surfactants have been widely used as effective additives to increase the solubility and dissolution rates of amorphous solid dispersions (ASDs). However, they may also generate adverse effects on the physical stability of ASDs. In this study, we systematically investigated the impacts of poloxamer,...