The Design and Synthesis of a New Series of 1,2,3-Triazole-Cored Structures Tethering Aryl Urea and Their Highly Selective Cytotoxicity toward HepG2

• Main Authors: Sittisak Oekchuae (Author), Jitnapa Sirirak (Author), Purin Charoensuksai (Author), Pawaris Wongprayoon (Author), Natthaya Chuaypen (Author), Jutatip Boonsombat (Author), Somsak Ruchirawat (Author), Pisit Tangkijvanich (Author), Apichart Suksamrarn (Author), Panupun Limpachayaporn (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Target cancer drug therapy is an alternative treatment for advanced hepatocellular carcinoma (HCC) patients. However, the treatment using approved targeted drugs has encountered a number of limitations, including the poor pharmacological properties of drugs, therapy efficiency, adverse effects, and...