Understanding the implication of Kawakita model parameters using in-die force-displacement curve analysis for compacted and non-compacted API powders

• Main Authors: Iyad Rashid (Author), Rula Raji Haddadin (Author), Ashaar Abdulsalam Alkafaween (Author), Rawan Nayef Alkaraki (Author), Rehan Mohammad Alkasasbeh (Author)
• Format: Book
• Published: SpringerOpen, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The aim of this study was to investigate powder mechanics upon compression using data obtained from force-displacement (F-D) curves. The Kawakita model of powder compression analysis was adopted in order to compare the pressure-volume reduction relationship of the drug powders in relation t...