γ-Glutamyl-Transpeptidase-Resistant Glutathione Analog Attenuates Progression of Alzheimer's Disease-like Pathology and Neurodegeneration in a Mouse Model
Oxidative stress in Alzheimer's disease (AD) is mediated, in part, by the loss of glutathione (GSH). Previous studies show that γ-glutamyl transpeptidase (GGT)-resistant GSH analog, Ψ-GSH, improves brain GSH levels, reduces oxidative stress markers in brains of APP/PS1 transgenic mice, a mouse...
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Autori principali: | Ye In Christopher Kwon (Autore), Wei Xie (Autore), Haizhou Zhu (Autore), Jiashu Xie (Autore), Keaton Shinn (Autore), Nicholas Juckel (Autore), Robert Vince (Autore), Swati S. More (Autore), Michael K. Lee (Autore) |
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MDPI AG,
2021-11-01T00:00:00Z.
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