Mechanisms of ring chromosome formation, ring instability and clinical consequences

• Autores principales: Guilherme Roberta S (Autor), Ayres Meloni Vera F (Autor), Kim Chong A (Autor), Pellegrino Renata (Autor), Takeno Sylvia S (Autor), Spinner Nancy B (Autor), Conlin Laura K (Autor), Christofolini Denise M (Autor), Kulikowski Leslie D (Autor), Melaragno Maria I (Autor)
• Formato: Libro
• Publicado: BMC, 2011-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The breakpoints and mechanisms of ring chromosome formation were studied and mapped in 14 patients.</p> <p>Methods</p> <p>Several techniques were performed such as genome-wide array, MLPA (Multiplex Ligation-D...