Synthesis, ADMET Properties, and In Vitro Antimicrobial and Antibiofilm Activity of 5-Nitro-2-thiophenecarbaldehyde N-((E)-(5-Nitrothienyl)methylidene)hydrazone (KTU-286) against <i>Staphylococcus aureus</i> with Defined Resistance Mechanisms

• Main Authors: Povilas Kavaliauskas (Author), Birute Grybaite (Author), Vytautas Mickevicius (Author), Ruta Petraitiene (Author), Ramune Grigaleviciute (Author), Rita Planciuniene (Author), Philip Gialanella (Author), Alius Pockevicius (Author), Vidmantas Petraitis (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The emergence of drug-resistant <i>Staphylococcus aureus</i> is responsible for high morbidity and mortality worldwide. New therapeutic options are needed to fight the increasing antimicrobial resistance among <i>S. aureus</i> in the clinical setting. We, therefore, character...