Semen Cuscutae flavonoids activated the cAMP-PKA-CREB-BDNF pathway and exerted an antidepressant effect in mice

• Main Authors: Qianfeng Shao (Author), Yue Li (Author), Lin Jin (Author), Sheng Zhou (Author), Xiaowei Fu (Author), Tong Liu (Author), Guangbin Luo (Author), Shaohui Du (Author), Che Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundSemen Cuscutae flavonoids (SCFs) constitute a class of metabolites of Semen Cuscutae, a botanical drug that was recently found to have an anti-depression effect. This study aimed to evaluate the anti-depression effects of SCFs in chronic unpredictable mild stress (CUMS)-induced mice and to...